mixed-effects, piecewise linear regression models proc mixed procedure Search Results


90
ChangePoint Inc piecewise linear mixed effects model with a
Piecewise Linear Mixed Effects Model With A, supplied by ChangePoint Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/sigmoidal+mixed+model/10__1097_slash_hep__0000000000000605-90-35-42
Average 90 stars, based on 1 article reviews
piecewise linear mixed effects model with a - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
InContext Inc piecewise linear mixed effects (lme)
Piecewise Linear Mixed Effects (Lme), supplied by InContext Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/piecewise+linear+mixed+effects++lme+/pm39609257-47-8-14
Average 90 stars, based on 1 article reviews
piecewise linear mixed effects (lme) - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
COMSOL Inc multiphysics piecewise function
Multiphysics Piecewise Function, supplied by COMSOL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/multiphysics+piecewise+function/10__3390_slash_en13164221-183-1-0
Average 90 stars, based on 1 article reviews
multiphysics piecewise function - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
OriginLab corp piecewise fitting function originpro 2018b
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Fitting Function Originpro 2018b, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/originpro+software/pmc06386598-30-0-13
Average 90 stars, based on 1 article reviews
piecewise fitting function originpro 2018b - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

96
MathWorks Inc appendix c piecewise modeling
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Appendix C Piecewise Modeling, supplied by MathWorks Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/Partial+Differential+Equation+Toolbox/oreluk_james_robert__2019__role_of_experimental_data_in_validating_and_quantifying_uncertainties_in_complex_physical_systems-446-7-15
Average 96 stars, based on 1 article reviews
appendix c piecewise modeling - by Bioz Stars, 2026-10
96/100 stars
  Buy from Supplier

90
Lawrence Livermore National Security LLC piecewise cubic interpolation methods
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Cubic Interpolation Methods, supplied by Lawrence Livermore National Security LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/piecewise+cubic+interpolation+methods/pm39413794-430-0-6
Average 90 stars, based on 1 article reviews
piecewise cubic interpolation methods - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Baier labs context-triggered piecewise-hashing
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Context Triggered Piecewise Hashing, supplied by Baier labs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/context+triggered+piecewise+hashing/10__1016_slash_j__diin__2019__01__027-191-8-12
Average 90 stars, based on 1 article reviews
context-triggered piecewise-hashing - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
COMSOL Inc piecewise cubic interpolation
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Cubic Interpolation, supplied by COMSOL Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/cubic+spline+interpolation/pmc10474164-128-11-6
Average 90 stars, based on 1 article reviews
piecewise cubic interpolation - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
MapleSoft Inc piecewise spline curve maple 11
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Spline Curve Maple 11, supplied by MapleSoft Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/piecewise+spline+curve+maple+11/pmc02566871-188-7-12
Average 90 stars, based on 1 article reviews
piecewise spline curve maple 11 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
OriginLab corp piecewise linear fitting
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Linear Fitting, supplied by OriginLab corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/piecewise+linear+fitting/pmc07461152-140-14-20
Average 90 stars, based on 1 article reviews
piecewise linear fitting - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
AUTODOCK GmbH energy (piecewise linear potential (plp)) torsion energy
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Energy (Piecewise Linear Potential (Plp)) Torsion Energy, supplied by AUTODOCK GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/energy++piecewise+linear+potential++plp+++torsion+energy/10__35652_slash_igjps__2022__12006-540-15-15
Average 90 stars, based on 1 article reviews
energy (piecewise linear potential (plp)) torsion energy - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Heindl GmbH piecewise quadratic c1 functions of two variables
Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function <t>(pwl2s)</t> consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.
Piecewise Quadratic C1 Functions Of Two Variables, supplied by Heindl GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mixed-effects%2C+piecewise+linear+regression+models+proc+mixed+procedure/piecewise+quadratic+c1+functions+of+two+variables/10__1007_slash_s11425___020___1882___6-420-14-8
Average 90 stars, based on 1 article reviews
piecewise quadratic c1 functions of two variables - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function (pwl2s) consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.

Journal: Cell chemical biology

Article Title: 14-helical β-Peptides Elicit Toxicity against C. albicans by Forming Pores in the Cell Membrane and Subsequently Disrupting Intracellular Organelles

doi: 10.1016/j.chembiol.2018.11.002

Figure Lengend Snippet: Binding isotherms of NBD-labeled β-peptides (0.2 µM) to (A) PC:PE (60:40), (B) PC:PG (60:40) and (C) PC:PE:ergosterol (50:30:20) SUVs ([lipid] = 5 to 2000 µM) with the indicated compositions after 2 min incubation. Xb* represents the molar ratio of bound peptide per 60% of total lipid and Cf is the equilibrium concentration of free peptide in solution. The partition coefficient is the slope of the binding isotherm and the critical concentration is the intersection of the low-slope and high-slope isotherms, shown in the insets. The placement of asterisk (*) near a data point indicates conditions at which vesicle aggregation was observed visually (see text). Data points represent the averages of three independent experiments and error bars denote standard deviation (n = 3). Lines in A, B, and C show linear and non-linear (piecewise fit lines by piecewise fitting function (pwl2s) consisting of two linear segments) data fits. The statistical data for each fit are: red line in A (non-linear fit, p = 0.0014, R2 = 0.85, intercept = 14.8 nM), black line in A (non-linear fit, p = 7.82 × 10−5, R2 = 0.87, intercept = 14.3 nM), blue line in A (linear fit, p = 1.71 × 10−11, R2 = 0.98); red line in B (non-linear fit, p = 1.51 x= 10−6, R2 = 0.96, intercept = 11.3 nM), black line in B (non-linear fit, p = 1.13 × 10−5, R2 = 0.91, intercept = 14.1 nM), blue line in B (non-linear fit, p = 5.89 × 10−4, R2 = 0.80, intercept = 13.0 nM); red line in C (linear fit, p = 9.33 × 10−7, R2 = 0.98), black line in C (linear fit, p = 5.83 × 10−8, R2 = 0.98), blue line in C (linear fit, p = 3.00 × 10−13, R2 = 0.99). See also Figures S4 and S5, and Tables S3 and S4.

Article Snippet: pwl2s; piecewise fitting function consisting of two linear segments , OriginPro 2018b , https://www.originlab.com/doc/Tutorials/Fitting-Piecewise-Linear.

Techniques: Binding Assay, Labeling, Incubation, Concentration Assay, Standard Deviation

Key Resource Table

Journal: Cell chemical biology

Article Title: 14-helical β-Peptides Elicit Toxicity against C. albicans by Forming Pores in the Cell Membrane and Subsequently Disrupting Intracellular Organelles

doi: 10.1016/j.chembiol.2018.11.002

Figure Lengend Snippet: Key Resource Table

Article Snippet: pwl2s; piecewise fitting function consisting of two linear segments , OriginPro 2018b , https://www.originlab.com/doc/Tutorials/Fitting-Piecewise-Linear.

Techniques: Recombinant, Software, Cell Culture